COMPUTATIONAL DRUG REPOSITIONING FOR PERIPHERAL ARTERIAL DISEASE: PREDICTION OF ANTI-INFLAMMATORY AND PRO-ANGIOGENIC THERAPEUTICS

Computational Drug Repositioning for Peripheral Arterial Disease: Prediction of anti-inflammatory and pro-angiogenic therapeutics

Peripheral arterial disease (PAD) results from atherosclerosis that leads to blocked arteries and reduced blood flow, most commonly in the arteries of the legs.PAD clinical trials to induce angiogenesis to improve blood flow conducted in the last decade have not succeeded.We have SUNGLASSES recently constructed PADPIN, protein-protein interaction n

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A novel mode of cytokinesis without cell-substratum adhesion

Abstract Cytokinesis is a final step in cell division.Dictyostelium cells, a model organism for the study of cytokinesis, have multiple modes, denoted cytokinesis A, B, C, and D.All these modes have been mainly investigated using cells adhering to the substratum although they can grow in shaking suspension culture.Here, we observed how cells divide

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